Glomerular Disorders

Think of these things when you are investigating intrinsic renal failure.

FeNa < 1%, sodium retention, urine osm high (urine osm low in ATN)
Check 24 hr urine protein


NEPHRITIS
proteinuria
dysmorphic RBCs in urine
RBC casts
WBC casts granular material

Low complement levels - post streptococcal GN, endocarditis, lupus nephritis, & cryo)

Post streptococcal
- subepithelial deposit, humps
- C3, CH50 low for 6-8 wks
- 14 day latency after throat, skin infection
- usually no chronic RF
- check ASO titers
- treat with abx

Nl complement levels- Henoch-Schonlein, IgA nephropathy, Goodpastures, Wegeners

Will finish soon.